Page 95 - Abstract Book KONIKA 18

Nutrition & Metabolic Diseases

O–NMD-007
Nutritional Status and Cardiovascular Risk
of Children with Nephrotic Syndrome

Natharina Yolanda, Ronald Rompies, Adrian Umboh
Department of Child Health, Faculty of Medicine Universitas of Sam Ratulangi/Prof. R.D. Kandou General Hospital,
Manado, North Sulawesi, Indonesia

Abstract
Background There is increased risk of protein-energy malnutrition and dyslipidaemia in children with
nephrotic syndrome. Treatment of nephrotic syndrome with prednisone increased the risk of overweight/
obesity and metabolic syndrome. Objectives To assess the nutritional status and cardiovascular risk of children
with nephrotic syndrome. Methods A case-control study was carried out in children aged 5-15 years old with
nephrotic syndrome treated at Pediatric Nephrology Outpatient Clinic, Prof. R.D. Kandou General Hospital
Manado in January-December 2020.Controls were apparently healthy children who presented to General
Pediatric Outpatient Clinic for minor illnesses. Weight, height, waist and hip circumference were measured
and plotted into appropriate growth curve to determine the nutritional status. Waist-to-hip ratio (WHR)
between two groups were compared to determine cardiovascular risk factor. Results A total of 58children
with nephrotic syndrome were recruited as cases and 30 children as controls. The median weight of cases
versus control was 25.13±10.45kg vs. 26.06±11.25kg and mean body mass index was 19.10 ±2.60 kg/m
2
vs.16.42 ±2.23kg/m . There was statistically significant difference in term of stunting (10% vs. 4%, P=0.012),
2
overweight (12% vs. 6%, P=0.033), and obesity (8% vs. 2%, P=0.020) between children with nephrotic
syndrome and controls, respectively. Incidence of underweight between two groups was not significant. WHR
was significantly higher in nephrotic syndrome group compared to control group (P=0.001). Conclusion
Children with nephrotic syndrome are prone to growth impairment and have higher cardiovascular risk
compare to those without nephrotic syndrome.
Keywords: cardiovascular risk; nephrotic syndrome; stunting; waist-to-hip ratio

KONIKA XVIII Abstract Book 49