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Nutrition & Metabolic Diseases

                                              O-NMD–005
                                   Low Sodium and Albumin Level:
                Its Association with Outcomes of Severe Acute Malnutrition Management
                              at RSUP Dr. Mohammad Hoesin Palembang

                                Ika Dian Puspitanza, Moretta Damayanti, Julius Anzar
              Department of Child Health, Faculty of Medicine Universitas Sriwijaya/Dr. Mohammad Hoesin General Hospital,
                                      Palembang, South Sumatera, Indonesia

                                               Abstract
            Background  Successful management of severe acute malnutrition (SAM) may be influenced by many
            factors, including abnormal laboratory findings in the early phase of hospitalization. Previous studies showed
            that exceptional laboratory results, such as anaemia, leukopenia, electrolytes imbalance and acidosis, in
            association with SAM outcomes, varied. Objective To analyse the association between laboratory profiles
            at the beginning of hospitalization and outcome of SAM management at RSUP dr. Mohammad Hoesin
            Palembang (RSMH). Methods It was a cross-sectional study reviewing medical records of SAM patients
            hospitalized between July 2020 until June 2021. The outcomes were mortality rate and mean weight gain
            during treatment categorized as insufficient (<5 g/kg/day) and sufficient (≥5 g/kg/day). Results  There were
            146 subjects with median age 33 (1-215) months and median length of stay 13 (1-42) days. Haematology
            profiles showed anaemia in 44.5%, leukopenia 12.3%, leukocytosis 44.5%, thrombocytopenia 21.9% and
            thrombocytosis 21.9%. Elevated C-reactive protein and hypoalbuminemia were identified in 38.4% and 17.8%,
            respectively. Electrolyte profiles revealed hyponatremia in 23.3%,hypokalemia 15.1%, hypomagnesemia
            1.4% and hypophosphatemia 6.2%. The mortality was 8.9% and significantly associated with hyponatremia
            (P=0.04;OR 3.58; 95%CI 1.06 to 12.07) and hypoalbuminemia (P=0.03;OR 3.70; 95%CI 1.07 to 12.78).
            The median weight gain was 3.59 (-12.6-31.75) g/kg/day and showed no relationship with any laboratory
            profiles. Conclusion Haematology and electrolytes abnormalities are common in SAM patients, as in this
            study where hyponatremia and hypoalbuminemia are significant factors for the mortality.
                        Keywords: hyponatremia; hypoalbuminemia; mortality; severe acute malnutrition
                                              O–NMD–006
               The Accuracy of Screening Tool for Risk of Impaired Nutritional Status and
                Growth (STRONGkids) for Detection of Nutritional Risk in  Hospitalized
                                  Pediatric Patients: A Meta-Analysis

                                Hanum Ferdian, Sandi Nugraha, Andhika Trisna Putra
                Department of Child Health, Faculty of Medicine Sebelas Maret Universitas/Dr. Moewardi General Hospital,
                                        Surakarta, Central Java, Indonesia

                                               Abstract
            Background Early detection of nutritional risk in hospitalized pediatric patients is important to ensure an
            early dietary intervention can be given. Therefore, it is critical to implement a universal screening method
            to achieve this purpose. Currently there is still no consensus on the recommended choice of instrument for
            nutritional risk screening in pediatric patients. Objective To evaluate the accuracy of  Screening Tool for
            Risk of Impaired Nutritional Status and Growth (STRONGkids) as a tool for screening pediatric nutritional
            risk. Methods Search query was conducted on PubMed, Scopus, ScienceDirect, EBSCOhost, ProQuest and
            Cochrane Library following PRISMA guidelines using the relevant keywords without limit on publication
            year. Original studies published in English evaluating the sensitivity and specificity of STRONGkids as a
            screening tool for pediatric nutritional risk or pediatric acute and/or chronic malnutrition were included.
            Results A total of 276 articles were found, ten of which were considered eligible. Analysis on the results of
            3,243 samples across all studies found that STRONGkids had a cumulative sensitivity of 78% (CI 97.5% =
            59.4%-89.5%) and a cumulative specificity of 63.7% (97.5%CI 39.8 to 82.3%). Conclusion STRONGkids
            showed high sensitivity and average specificity in early detection of nutritionally at-risk or acutely and/
            or chronically malnourished pediatric patients. Its application in the hospital setting supported by proper
            protocols of care could be beneficial and is recommended.
                             Keywords:  STRONGkids; nutritional risk; pediatric; malnutrition

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