Page 340 - Abstract Book KONIKA 18

Neurology

P-NEU-007
Effect of Exclusive Breastfeeding
on the Neurological Development of Children 6-24 Months: Case-Control Study

Armitha Putri, Irawan Mangunatmadja
Department of Child Health, Faculty of Medicine Universitas Indonesia/Dr. Cipto Mangunkusumo General Hospital,
Jakarta, Indonesia

Abstract
Background Sustainable Development Goals (SDGs) are the government's commitment in the National long
term plan in Indonesia related to child development. Child nutrition problems in Indonesia tend to increase
every year. Children who do not get exclusive breast milk will be more susceptible to health problems in
the future and can be fatal for child’s health. Based on WHO recommendation, exclusive breastfeeding for
6 months. This study discusses about the relationship between exclusive breastfeeding and neurological
development of children 6-24 months. Objective To identify the role of exclusive breastfeeding and non-
exclusive breastfeeding (breast milk and formula) in predicting delay in neurological development of children
6-24 months. Methods A case control study for children 6-24 months in Poli Neurologi Anak Departemen
Ilmu Kesehatan Anak FKUI-RSCM (RSUPN Cipto Mangunkusumo) Jakarta dan Klinik Anakku Pondok
Pinang Center Jakarta Selatan (in English) from March to May 2021. The data was collected from parental
interviews and observations with the subjects. Data were processed with SPSS statistics for windows and
analyzed by Chi-square test and logistic regression method. Results The total number of subjects in these
research was 140 children, 70 children with exclusive breastfeeding and 70 children with non-exclusive
breastfeeding. Delay in neurological development in exclusive breastfeeding is lower than non-exclusive.
In the multivariate analysis, the significant variables are the early ages of exposure gadget (P=0.001; OR
3.140; CI 1.603 to 6.883). Conclusion There are no significant effect between exclusive breastfeeding on
children’s neurological development, and there are a significant effect between the early ages of exposure
gadget by exclusive breastfeeding for children 6-24 months.
Keywords: exclusive breastfeeding; neurological development; children 6-24 months

P-NEU-008
Congenital Toxoplasmosis in Infant: A Case Report

Christina Silalahi, Prastiya Indra Gunawan, Darto Saharso, Riza Noviandi
Department of Child Health, Faculty of Medicine Universitas Airlangga/Dr. Soetomo General Academic Hospital,
Surabaya, East Java, Indonesia

Abstract
Background Congenital toxoplasmosis is another form of toxoplasmosis defined by the vertical transmission
of Toxoplasma gondii tachyzoites parasite from an infected pregnant woman to the fetus through the placenta.
Congenital toxoplasmosis is an infection disease rarely found in Indonesia, especially in Surabaya. It was
estimated that 40% of infected infants underwent spontaneous abortion and abnormal conditions, and the
remaining 60% had asymptomatic clinical manifestations. Objective To present a rare case of infant with
congenital toxoplasmosis Case A two-month-old baby girl was referred to the emergency department at Dr.
Soetomo General Academic Hospital with a chief complaint of seizures, vomiting, and fever intermittently
for two weeks. The physical examination revealed that she was lethargic, had chorioretinitis, an open
and bulging anterior fontanel, and also hepatomegaly. The head CT scan revealed active communicating
hydrocephalus and intracranial calcifications. These manifestations were supported by positive IgG and
IgM Toxoplasma serological results, which confirmed the diagnosis. The baby underwent an urgent external
ventricular drain (EVD) procedure to reduce intracranial pressure. The combination of pyrimethamine and
sulfadiazine regimens was considered to give, but unfortunately, the baby died due to respiratory failure.
Conclusion Congenital toxoplasmosis is a rare case with a poor prognosis. The diagnostic approach is based
on clinical findings, serological screening of anti-Toxoplasma antibodies and head CT scan. The treatment
of the infected fetus with pyrimethamine and sulfadiazine regimens should be given immediately and CSF
shunting is required for the treatment of hydrocephalus.
Keywords: congenital toxoplasmosis; chorioretinitis; hydrocephalus; disease

292 KONIKA XVIII Abstract Book