Page 344 - Abstract Book KONIKA 18

Neurology

P-NEU-015 (Prime e-Poster)
Quality of Life Comparison in Children Diagnosed with Epilepsy More Than
Two Years and Less Than or Equal to Two Years

Ivan Halim, Nurhayati Masloman, Praevilia M. Salendu, Sarah M. Warouw, Gracia Deswita
Department of Child Health, Faculty of Medicine Universitas Sam Ratulangi/Prof. dr. R. D. Kandou Hospital, Manado,
North Sulawesi, Indonesias

Abstract
Background Epilepsy is a chronic neurological disease that often occurs in children and has the potential
to cause various problems, including learning difficulties, developmental disorders and decreased quality
of life. Epilepsy is associated with intellectual deficits and behavioral problems related to the duration of
the disease and the frequency of seizures, where these conditions will affect the physical and psychological
morbidity of the child. Objective To determine the difference of quality of life in children diagnosed with
epilepsy more than two years and less than or equal to two years. Methods This cross-sectional study
(comparative analytic observational study) from February – April 2019, involved children aged 2-18 years
who has been diagnosed with epilepsy and then divided into two groups, patients diagnosed with epilepsy
more than two years, and less than or equal to two years. Quality of life were measured by Pediatric Quality
of Life Inventory (PedsQLTM) Epilepsy Module Version 3.0 questionnaire which both patients and their
parents completed. Results Forty-four children were divided into 2 groups, the quality of life in children
diagnosed with epilepsy greater than two years (mean 80.36%) is better than in children less than or equal
to two years (mean 55.44%). The Mann-Whitney U test result obtained a value of Z = -4.652 with P value
< 0.001. Conclusion Quality of life in children diagnosed with epilepsy for more than two years is better
than diagnosed less than or equal to two years.

Keywords: epilepsy; children; quality of life

P-NEU-016
Atrial Myxoma in Probable Anti-NMDAR Encephalitis Patient
in Sanglah Hospital, Bali, Indonesia: A Case Report

I Gusti Ngurah Agung Jayadhi Widyakusuma, I Gusti Ngurah Made Suwarba
Department of Child Health, Faculty of Medicine Universitas Udayana/Sanglah General Hospital,
Denpasar, Bali, Indonesias

Abstract
Background Anti-NMDAR encephalitis is an immune-mediated disease characterized by a complex
neuropsychiatric syndrome and the presence of CSF antibodies against the GluN1 subunit of the NMDAR.
Myxomas are rare primary benign cardiac tumors of all primary benign cardiac tumors in children. Myxomas
may be associated with immune-mediated mechanisms and paraneoplastic syndrome (PNS). Objective To
describe a case of atrial myxoma in probable anti NMDAR encephalitis female diagnosed after showing
specific clinical presentation, and conflicting laboratory results. Case A 17-year-old girl was referred to
Sanglah Hospital, with a chief complaint decreased of consciousness since 12 hours before admission. The
patient had stiff extremities and body, both eyes glared up, and was unconscious. During hospitalization she
started agitated, then she was lack of communication and interpersonal contact. She was unable to perform
the cognitive function. She could not recognize her surroundings and relatives. The patient had a normal
complete blood count, electrolyte and renal function test. A head CT scan showed lesion mild hyperdense intra
axial at subcortical parietalis lobus and mild heterogeneous contrast enhancement, suspect early cerebritis,
subacute cerebral infarction at left basal ganglia. Anti-NMDAR serum was negative. Echocardiography
showed a mass at left atrium with left ventricle inflow obstruction due to suspect libman-sacks endocarditis
differential diagnose myxoma differential diagnose thrombus. The patient was treated with high-dose
methylprednisolone, cyclophosphamide, and corticosteroids. Conclusion Anti-NMDAR encephalitis is a
disease with a challenging diagnosis of neuropsychiatric syndrome in children. Myxomas may be associated
with immune-mediated mechanisms. Early diagnosis, comprehensive and multidisciplinary management is
required for a better outcome.
Keywords: anti-NMDAR encephalitis; myxoma

296 KONIKA XVIII Abstract Book