Page 307 - Abstract Book KONIKA 18

Neonatology

P-NEO-039
The Relationship of Procalcitonin Serum Level to The Mortality of Neonatal
Sepsis in NICU in Prof. DR. R.D. Kandou Hospital Manado

Nicholas Hartanto Prawoto, Rocky Wilar, Johnny Rompis
Department of Child Health, Prof. Dr. R. D. Kandou Hospital, Universitas Sam Ratulangi,
Manado, North Sulawesi, Indonesia

Abstract
Background Neonatal sepsis still becomes the major problem and causes mortality in neonates. Procalcitonin
is an excellent marker for severe, invasive bacterial infection in neonatal sepsis. Objective To identify the
relationship between procalcitonin Serum level to the mortality in neonatal sepsis. Methods This cross
sectional study was performed from medical record data from all neonates diagnosed with neonatal sepsis
in neonatal intensive care unit, Prof. DR. R. D. Kandou Hospital Manado,from January 2021 to June 2021.
The relationship of procalcitonin serum level to the mortality in neonatal sepsis was measured by Mann
Whitney test. Results There were 30 neonates with sepsis as the subjects, There were 18 neonates (60%)
with preterm birth, and 12 neonates (40%) with aterm birth, the mean of birth weight is 2,09 kg, The mean
of procalcitonin level was 19,82 ng/mL. Among 30 neonates with sepsis neonatal admitted to neonatal
intensive care unit, and the 21 (70%) were died, the average lenght of treatment for neonatal sepsis was
12.8 days. Statistical analysis showed that the higher procalcitonin level were significantly associated with
mortality in neonatal sepsis (P=0.015). There is no association between procalcitonin levels and mortality
distinguished in neonatal with aterm or preterm birth (P=0.341). Conclusion The higher procalcitonin level
were significantly associated with mortality in neonatal sepsis There is no association between procalcitonin
levels and mortality in neonatal with aterm or preterm birth.
Keywords: procalcitonin; neonatal sepsis; mortality

P-NEO-040
Clinical And Laboratory Profiles of Preterm Baby who Received Surfactant
in NICU Prof. Dr. R. D. Kandou Hospital Manado

Indah Megawati, Rocky Wilar, Johnny Rompies, Shekina H. E. Rondonuwu
Department of Child Health, Faculty of Medicine Universitas Sam Ratulangi/Prof. Dr. R. D. Kandou Hospital,
Manado, North Sulawesi, Indonesia

Abstract
Background Many preterm babies born with respiratory distress due to the prematurity of the lungs and
deficient in surfactant. Objective To review the profile of preterm baby who got surfactant such as type of
respiratory distress, the use of respiratory machine, clinical manifestations, laboratories, and survival pattern.
Methods This was a retrospective observational study at NICU of Prof. R. D. Kandou Hospital, Manado,
from January 2020 to June 2021. We review all the preterm baby that was born <37 weeks gestational age.
Results We review a total of 344 preterm baby medical records admitted from January 2020 to June 2021,
with 33 preterm babies (9,5%) got surfactant. They were divided in 3 gestational age: 3 moderate to late
preterm babies (32-36 GA), 17 very preterm babies (28-31 GA) and 13 extremely preterm babies (<28 GA).
Most of them born spontaneously (70%), from mother with age >30 years old (51%) and received ventilator
support (75%). The clinical manifestations that found were cholestasis 10%, GIT Bleeding 42%, respiratory
distress 81%, congenital heart disease 12% (4 PDA, 1 ASD). From laboratories found were the leukocytosis >
20.000 48%, elevated CRP 48%, and blood culture was found positive of Enterobacter cloacae complex and
Klebsiella pneumonii. Conclusion Respiratory distress, GIT bleeding, leukocytosis and elevated CRP are the
most common clinical and laboratory profiles found in premature infants receiving surfactant at our place.
Keywords: preterm baby; surfactant; NICU

KONIKA XVIII Abstract Book 259