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Neonatology
P-NEO-030
Case Report: Neonatal Multisystem Inflammatory Syndrome
Associated with Maternal SARS-CoV-2 Exposure
Ressa Hana Natasa Peranginangin, Adhi Teguh Perma Iskandar, Mulya Rahma Karyanti,
Dedi Wilson, Ivan Rizal Sini , Ariani Dewi Widodo
Bunda Women and Children Hospital Jakarta, Indonesia
Abstract
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly infectious, with
multiple possible routes of transmission. Although vertical transmission has not yet been established, neonatal
multisystem inflammation may occur secondary to maternal SARS-CoV-2 infection due to transplacental
transfer of antibodies. Objective To demonstrate a case of multisystem inflammatory syndrome in neonates
(MIS-N) secondary to maternal SARS-CoV-2 infection. Case A full-term male neonate, weighing 4007g,
was delivered by caesarean section due to breech presentation. The mother was asymptomatic and tested
positive for SARS-CoV-2 just before delivery. Upon delivery, the baby had significant bradycardia and
required positive pressure ventilation (PPV) for 3 minutes. Apgar scores were 7 and 9 at 1 and 5 mins.
The baby was tested negative twice on RT-PCR. At 48h of life, he developed sinus bradycardia and skin
rash. Echocardiogram did not reveal any abnormalities. Serum investigations showed elevated CRP level
(7.4mg/L), D-dimer (2.35mg/mL) and Troponin I (103.4pg/mL). The infant was diagnosed with MIS-N.
Treatment included one course of intravenous immunoglobulin (1 g/kg/dose) and a course of intravenous
methylprednisolone (1 mg/kg every 8h for 3 days) were administered. On the 7th day of life, the infant
no longer showed any symptoms and laboratory parameters improved. Then, the baby was discharged.
Conclusion Neonatal multisystem inflammatory syndrome may occur secondary to maternal SARS-CoV-2
infection and may be severe depending on each individual response. As many pregnant women are infected
with SARS-CoV-2, neonates born from those mothers should be closely monitored and may need a thorough
clinical and laboratory evaluation.
Keywords: neonatal; SARS-CoV 2; MIS-N
P-NEO-031
The Association between Mother’s Knowledge and Attitude
towards Intention to Breastfeed during Pandemic
Ressa Novita Afandi, Putu Fristia Indarini, Saskia Octariza
Asih Women and Children Hospital, Jakarta, Indonesia
Abstract
Background During the first six months of life, breast milk is ideal for meeting the nutritional needs of
infants. In Indonesia, there are only 37,3% infants who exclusively breastfeed for 6 months. World Health
Organization suggests continuing breastfeeding while wearing personal precaution equipment and maintaining
distance during pandemic. Mother’s decision not to breastfeed her baby had a long-term effect on child and
mother health, child nutrition and child development. Knowledge and attitude are two factors affecting
mother’s decision to breastfeeding. Objective To explore the parental knowledge, attitude, and intention to
exclusive breastfeed during pandemic and the association between those variables. Methods A cross-sectional
study was conducted at Asih Women and Children Hospital in August 2020. Pregnant mothers who visiting
outpatient clinic were chosen by consecutive sampling filling questionnaires contained identity, knowledge,
attitude and intention to exclusively breastfeed. Chi-square test was used to analyze the association.
Results Among 136 subjects, most of them were between 26-30 years of age (52.2%) and working women
(68.4%). In general, most of subjects had a good knowledge (73.5%), positive attitudes (80.1%), and intended
to exclusive breastfeed their baby (85.3%). There was no significant association between mother’s knowledge
towards intention (P = 0.138) to exclusively breastfeed while association between mother’s attitudes with
intention (P=0.000) to exclusively breastfeed was significant.Conclusion Mother’s attitude influences
breastfeeding decisions. Breastfeeding intervention during this pandemic is needed to create positive attitudes
thus, resulting higher breastfeeding intention and greater efforts of sustenance of breastfeeding.
Keywords: breastfeeding; pandemic; knowledge; attitude
254 KONIKA XVIII Abstract Book

