Page 312 - Abstract Book KONIKA 18

Neonatology

P-NEO-048
Characteristics of Newborn in COVID-19 Confirmed and Its Neurodevelopment:
A Serial Cases

Cahyani Chrishariyati, Brigitta I. R. V. Corebima, Eko Sulistijono, Setya Mithra Hartiastuti
Department of Child Health, Faculty of Medicine Universitas Brawijaya/Saiful Anwar Hospital,
Malang, East Java, Indonesia

Abstract
Background The novel Coronavirus disease 2019 caused by severe acute respiratory syndrome Coronavirus
2 (SARS-CoV-2) has spread exponentially across the globe. During the COVID 19 pandemic, pregnant
women and newborns represent a vulnerable population. Since the first reported case of neonatal COVID-19
in February 2020, concerns about possible vertical transmission of SARS-CoV-2 have been raised, but it
is unclear if COVID-19 can cross through the transplacental route to the fetus. Objective To describe the
characteristics and neurodevelopment of newborn with confirmed covid 19. Results From 28 mother with
aterm pregnancy (average 36-38 weeks) who were confirmed by COVID-19, there were 4 newborns with
confirmed COVID-19 from the PCR swab in Saiful Anwar Hospital. Their mother were asymptomatic
at the time admission but with PCR swab results confirmed covid 19. The four newborn baby were born
SCTP with an average APGAR score of 6-8 and crying immediately and asymptomati. The babies were
born with average of birth weight was 2900 grams. During at home the baby sleep separately and getting
full breast milk with the mother still using health protocols. Currently, Infant growth is measured using
the WHO curve at the mean until +2 SD and for development using KPSP with appropriate conclusions.
Conclusion This case series support the hypothesis that in utero SARS COV 2 vertical transmission, while
low, is possible. Although with confirmed covid 19, the babies with good growth and development even with
breastfeeding. Based on this, breastfeeding is safe but still uses the right health protocol.
Keywords: COVID 19; transmission; breast milk; neurodevelopment; body weight

P-NEO-049
Gastrointestinal Abnormality in Newborn: A Systematic Review

2
1
1
Dimas Tri Anantyo , Ayu Anggraini Kusumaningrum , Kamilah Budhi Rahardjani ,
1
Arsita Eka Rini , Adhie Nur Radityo , Gatot Irawan Sarosa 1
1
Departement of Pediatrics and Medical Doctor , Faculty of Medicine, Universitas Diponegoro,
1
2
Semarang, Central Java, Indonesia
Abstract
Background Gastrointestinal abnormalities in newborns are the most common congenital abnormalities.
The incidence of congenital abnormalities in developed countries is found in 30% of all infants who are
hospitalized. The incidence of gastrointestinal tract abnormalities ranges from 1.3 in 1000 live births.
Gastrointestinal abnormalities cause a lot of morbidity and mortality in newborns. Early diagnosis and
detection of influencing factors are essential to prevent the occurrence of gastrointestinal abnormalities in
newborns. Methods Reviewed and summarized scientific literatures on Gastrointestinal Abnormalities in
newborns performed on PubMed, ScienceDirect, and Google Scholar to search for journals published in
January 2006-May 2021. From 20851 articles founded, 128 decent and quality full-text articles filtered, 37
excluded. 28 articles obtained. Results Based on a search of several journals found that there are risk factors
in the form of polyhydramnios that affects the incidence of gastrointestinal disorders in newborns such as
duodenal atresia and gastroschisis. There are also risk factors for maternal obesity, too young age (<20
years) and too old age (>35 years), history of smokers with smoking frequency ten pieces per day which
affects almost several gastrointestinal abnormalities. For screening, some gastrointestinal abnormalities
in newborns can be detected by ultrasound during the first trimester of pregnancy. Furthermore, the
diagnosis can be made by the thorax and abdominal x-ray, inventogram, and contrast enema radiograph on
the particular indication. Most of the gastrointestinal abnormalities in newborns are treated with surgery.
Conclusion The mother's condition affects the fetal development that occurs during pregnancy which will
affect congenital abnormalities, especially in gastrointestinal system.
Keywords: gastrointestinal abnormality; congenital disease

264 KONIKA XVIII Abstract Book