Page 77 - Abstract Book KONIKA 18

Infection & Tropical Diseases

O-ITD-003
Understanding Profiles and Outcomes of Children with COVID-19:
One Year Evaluation of the Pandemic in North Sumatera

3,4
1
1,2
Ayodhia Pitaloka Pasaribu , Andrew Limavady , Eka Airlangga , Ririe Fachrina Malisie 1,5
2
1
Department of Child Health, Medical Faculty, Universitas Sumatera Utara , Adam Malik General Hospital ,
4
3
Medical Faculty, Universitas Muhammadiyah Sumatera Utara , Bunda Thamrin Hospital , Murni Teguh Memorial
5
Hospital , Medan, North Sumatera, Indonesia
Abstract
Background Since December 2019, a cluster of viral pneumonia cases later identified as coronavirus disease
2019 (COVID-19) was first reported in Wuhan, China, then continues to spread to other parts of the world.
COVID-19 was thought to be more prevalent in adults compare to children, therefore information about its
burden and manifestation in children are lacking. Objective To evaluate profile and outcome of children with
COVID-19 confirmed in North Sumatera. Methods We gathered data on profile and outcome of children
with COVID-19 from medical record collected from 3 COVID-19 referral hospitals in Medan between April
2020 to March 2021. Data was presented as mean ± SD and percentage. Statistical analysis was performed
using STATA version 15.0. Results Within 1 year of the pandemic, there were 231 COVID-19 confirmed
children treated in 3 hospitals in Medan. About 45.02% of patients were above 10-year-old, however 9.09%
were children under 1 year old. Fever (73.59%) and cough (65.80%) were the two main symptoms occurred.
One third (30.74%) of the patients were with obesity and 2.16% patients were with hematological problems.
There were 8/231 (3.46%) patients died. No specific laboratory result was found; however, a high mean of
D-dimer (615.75 (SD± 129.99)) was predominant. Conclusion COVID-19 can affect children at any age
with fever and cough as major symptoms. Obesity and hematological problems found to be the leading
comorbidities. High number of children in this study died which increase knowledge that children with
COVID-19 are not always mild.
Keywords: children; COVID-19; profiles; outcomes; north sumatera

O-ITD-004
Malaria Infection was Associated with Poor Birth Outcomes
in a Remote Community of Sikari District: A Single Centered Study in
Mamberamo Raya Regency, Province of Papua, Indonesia
Deddy Christian Aritonang , Tri Wahyudi Iman Dantara 2
1
1
2
Batavia Public Health Center, Mamberamo Raya Regency and Biak General Hospital, Biak Numfor Regency ,
Province of Papua, Indonesia
Abstract
Background Sikari is a remote district, which is a malaria-endemic area. Several studies have reported
that malaria infection during pregnancy was linked to a poor birth outcome. Objective To determine the
association between malaria infection in pregnancy and birth outcome. Methods This is a retrospective
cohort study. Clinical data of 82 pregnant women was recorded from January-December 2020 at the Batavia
Health Center, Sikari District, Mamberamo Raya, Papua. Malaria diagnosis was established based on WHO
criteria with positive rapid diagnostic tests. Years of formal education, ANC visitation, gestational age,
obstetric history, diagnosis of malaria, newborn weight, APGAR score, and newborn mortality were analyzed.
Results We reported 46 patients (56.10%) diagnosed with malaria. 33 (71.7%) tropical malaria, 7 (15.2%)
tertian malaria, and 6 (13.0%) mixed malaria. All malaria infections were associated with an increased risk
of preterm birth (OR 30.25; 95%CI 3.59 to 254.73; P=0.00), low birth weight (LBW) (OR 19.60; 95%CI
11.12 to 34.53; P=0.00), newborn mortality (OR 22.5; 95%CI 3.93 to 128.95; P=0.00), and lower APGAR
(OR 52.90; 95%CI 9.65 to 290.05; P=0.00). We reported an association of tropical malaria with a higher risk
of preterm birth (OR 8.80; 95%CI 1.35 to 57.43; P=0.02), LBW (OR 28.00; 95%CI 2.82 to 277.96; P=0.00),
newborn mortality (OR 33.00; 95%CI 1.31 to 833.87; P=0.03), and lower APGAR (OR 55.86; 95%CI 2.53
to 123.12; P=0.00). Conclusion Malaria infections are associated with an increased risk of preterm birth,
low birth weight, newborn mortality, and lower APGAR in the remote Sikari District.
Keywords: poor birth outcome; malaria infection; remote area

KONIKA XVIII Abstract Book 31