Page 66 - Abstract Book KONIKA 18

Endocrinology

O-ENDO-003
Quality of Life Among Children with Osteogenesis Imperfecta
in the Era of Pandemic Covid-19

Rahma Ira Mustikasari, Nur Rochmah, Muhammad Faizi, Irwanto.
Department of Child Health, Faculty of Medicine Universitas Airlangga/Dr. Soetomo General Academic Hospital,
Surabaya, East Java, Indonesia

Abstract
Background Most chronic illnesses, such as Osteogenesis Imperfecta (OI), will be as stressors to children
and caregivers and can affect the Quality of Life (QoL). Pandemic COVID-19 has impacted on disruption of
health services and many patients cannot be routinely evaluated in healthcare systems. Objective To evaluate
the impact of pandemic COVID-19, on QoL in children with Osteogenesis Imperfecta Methods The study was
conducted at the time of pre-pandemic and during COVID-19 pandemic era. Quality of Life was evaluated
with Pediatric Quality of Life Inventory (PedsQL) 4.0 Generic Core in Endocrinology Outpatient Clinic at
Dr Soetomo Hospital. Results There were 22 patients with OI, 11/22 girls and 11/22 boys, age average was
6.9-year-old. The children who take the bone supplementation during pre-pandemic and pandemic era were
19/22 versus 14/22. There were 16/22 OI children having difficulty to access the hospital, 18/22 postpone
visited the hospital due to fear of contracting COVID-19, 6/22 due to community mobilization restriction
and other 6/22 due to their parents got job loss. The result showed that the average score of physical,
emotional, social and school functioning of PedsQL in pre-pandemic and pandemic era were 49.57, 63.41,
58.86 and 66.13 versus 42.76, 54.54, 53.86 and 56.74 respectively. There were significantly different in all
of functioning of PedsQL between pre and during pandemic COVID-19 (P<0.05). Conclusion Pandemic
COVID-19 reduces the QoL of children with Osteogenesis Imperfecta. Improving policy in hospital services
by providing outpatient clinic special for OI children will be beneficial.

Keywords: osteogenesis imperfecta; PedsQL; pandemic COVID-19

O-ENDO-004
Metabolic Control and Behavioral Disorders
among Children with Type 1 Diabetes Mellitus during Covid 19 Pandemic

Luh Ayu Asri Wijani, Muhammad Faizi, Nur Rochmah, Irwanto.
Department of Child Health, Faculty of Medicine Universitas Airlangga/Dr. Soetomo General Academic Hospital,
Surabaya, East Java, Indonesia
Abstract
Background Children with type 1 diabetes mellitus (T1DM) often experience emotional and behavioral
disorders. During Covid 19 Pandemic, in order to limit the spread, the government have ordered a serial of
social restrictions that may affect metabolic control, eventually this will impact emotional and behavioural in
children with T1DM. Objective To evaluate the impact of COVID-19 in metabolic control and behavioural
disorders among children with T1DM. Methods Cross sectional study was conducted from January to
August 2021. Samples were children from Out Patient Clinic Soetomo Hospital consists of good metabolic
control(HbA1C≤8) and poor metabolic control groups(HbA1C>8). PSC-17 was used as screening tool at
4-17year-old then determine into internalization disorder(ID), externalization disorder(ED), and attention
disorder(AD). The data were analyzed using Independent-T and Fisher test with p value <0.05 regarded as
significant. Results Twenty-seven participants were included in this study, 8 participants have good metabolic
control and 19 have poor. 4/27 (14.8%) have ID, 5/27 (18.5%) have ED and none of them have AD. Among
participants with good metabolic control, the frequency of ID;ED were 1/8 (12.5%); 3/8(37.5%). Among
participants with poor metabolic control, the frequency of ID;ED 3/19 (15.8%); 2/17 (10.5%). Comparing
between 2 groups, there were no significantly different (P=0.14). Conclusion During Covid 19 Pandemic,
there are more children have poor metabolic control than good metabolic control. Among children with
good metabolic control there are tendency to have ED, and among children with poor metabolic control
there are tendency to have ID.
Keywords: metabolic; behavioral; children; diabetes

20 KONIKA XVIII Abstract Book