Page 64 - Abstract Book KONIKA 18

Emergency & Pediatric Intensive Care

O-EPIC-007
Features, Management, and Outcomes of Severe-Critical Covid-19 in Children:
A Prospective Study

Charity Monica, Saptadi Yuliarto, Kurniawan Taufiq Kadafi
Department of Child Heatlh, Faculty of Medicine, Universitas Brawijaya Malang, East Java, Indonesia

Abstract
Background There is limited data about the outcomes of severe-critical covid-19 in Indonesian children.
Objective To compare clinical features, management, and outcomes of covid and non-covid children.
Methods This is a prospective study conducted in Saiful Anwar Hospital, April 2020 to May 2021. The
inclusion criteria were suspected, probable, or confirmed covid-19 children admitted to pediatric intensive
care unit (PICU). The observed parameters were clinical symptoms, comorbidities, laboratory parameters,
case management, complication, and outcomes. This study approved by the ethics committee of Universitas
Brawijaya. Results There were 71 patients, 16 were confirmed covid-19. The covid-19 children were older
than non-covid (mean: 64.9, SD 58,6 vs. 31.9, SD 53.1 months, respectively; P=0.035). There were no
differences of clinical symptoms, comorbidities, and laboratory results. Covid-19 children were more likely
to need invasive ventilation (62.5%) than non-covid (41.8%). The need of vasoactive agents were comparable
between 2 groups. Mean ventilator duration was 11.3 (SD 7.4) days and PICU stay was 13.2 (SD 9.8) days
were longer in covid-19 compared to non-covid group [4.8 (SD 3.4) days and 4.9 (SD 3.6) days, respectively)
(P<0,001). Acute respiratory distress syndrome (ARDS) and acute kidney injury (AKI) were most common
in covid-19 groups (P=0.02 and P=0.05, respectively). Mortality was higher in covid-19 (31.3 vs. 14.5%)
although was not statistically significant (P=0.32). Conclusion Covid-19 children were more likely to need
invasive ventilation, longer ventilator duration and PICU stay, also had more complications of ARDS and AKI.
Keywords: severe-critical covid-19; invasive ventilation; complications; mortality

O-EPIC-008
Comparison of PRISM IV and PELOD 2 Score as Predictor of Mortality
in Critically Ill Children in Haji Adam Malik General Hospital

Thomas Silaban, Aridamuriany D Lubis, Bugis M Lubis
Department of Child Health, Faculty of Medicine, Universitas Sumatera Utara/Haji Adam Malik General Hospital,
Medan, North Sumatera, Indonesia

Abstract
Background Critical illness is collection of conditions and disorders that have impact on the occurrence of
organ dysfunction, prolonged morbidity and mortality. Score of mortality objectively calculates the severity
of disease and predicts risk of mortality according to the clinical condition of patient. Today, no standardized
scoring system that used in PICU for initial assessment of patients in Indonesia yet. Objective To compare
mortality predictor ability between PRISM IV and PELOD-2 score as predictors of mortality in critically
ill children at Haji Adam Malik General Hospital Medan. Methods Prospective cohort study was conducted
in PICU of Haji Adam Malik General Hospital from September 2020 to March 2021. Characteristics of the
sample were obtained through the medical record of patients treated in PICU. Assessment of PRISM IV and
PELOD-2 score was carried out on the first and third days of patient being admitted in PICU. Results Of the
35 children who were treated, 15 (42.9%) children were treated with respiratory problems. There were 18
(51.4%) children died. It was found that there was no significant difference mean score of PRISM IV and
Pelod-2 score on first and third days of examination (P>0.05). It was also found that PRISM IV and Pelod-2
score could not predict mortality of children with critical illness on the first (AUC 49.7%; 57.2%) and third
days (AUC 65 .4%;69.3%,). Conclusion PRISM IV and PELOD-2 score on the first and third days could
not predict mortality of critically ill children at Haji Adam Malik General Hospital Medan.
Keywords: critically ill children; PRISM IV; PELOD-2

18 KONIKA XVIII Abstract Book