Page 211 - Abstract Book KONIKA 18

Gastroenterohepatology

P-GEH-003
Profiles of Liver Function on Neonatal Low Birthweight
at Prof. Dr. R.D Kandou Hospital Manado

David Wenas, Jeanette I. Ch. Manoppo
Department of Child Health, Faculty of Medicine Universitas Sam Ratulangi/ Prof . Dr. R.D. Kandou General Hospital
Manado, North Sulawesi, Indonesia

Abstract
Background Neonatal low birthweight is definition as infant who birthweight <2500 gram. SGOT and SGPT
abnormalities as well as hypoalbuminemia can be found in Neonatal low birthweight. Objective To obtain
the overview of liver function especially SGOT, SGPT and albumin in infant with low bodyweight and
accompanied neonatal sepsis at NICU of Prof. Dr. R. D. Kandou Hospital. Methods This was a retrospective
and descriptive study. Data were obtained from the patients’ medical records. Results The results showed
that the percentage of Neonatal low birthweight that had mild increased SGOT level was 33.9%. Meanwhile,
the SGPT level was more often normal (88.4%). Increased SGOT and SGPT levels were more likely a mild
increase, frequent in male infants 35.5% for mild increased SGOT whereas increase SGPT more frequent
in female infants 6.5% for mild increased SGPT. Hypoalbuminemia was found in 63 infants (40.9%), more
frequent in male infants (46.3%). Hypoalbuminemia is more common in low birthweight infants with neonatal
sepsis (88.4%). Conclusion Among neonatal low birthweight increased SGOT levels were more often in
mild form meanwhile increased SGPT levels were rare. Increased SGOT and SGPT levels and decreased
albumin levels were more common among male infants and neonatal sepsis.
Keywords: SGOT; SGPT; albumin; neonatal sepsis; neonatal low birth weight

P-GEH-004
Recurrent Intussuception in 2-year-old Baby: A Case Report

2
Dian Yosie Monica , Martinus M. Leman , Veronica R. Manurung 3
1
2
Emergency Department , Department of Child Health , and Department of Pediatric Surgery ,
3
1
Sentra Medika Hospital, Cibinong, West Java, Indonesia
Abstract
Background Intussusception refers to the invagination of part of the intestine into its distal part. It can cause
ischemic necrosis in intestines which lead to perforation and peritonitis. Intussusception is the most common
cause of acute intestinal obstruction in infants and young children. Objective To report case of recurrent
intussusception in 2-years old baby. Case A 15-months old baby girl was admitted due to frequent vomitus. She
was alert with stable vital signs, but looked dehydrated. The next day, she vomited more frequently and had
red currant jelly stool. The abdomen was distended and tender, increased bowel sound without metallic sound,
and positive dance’s sign. The abdominal X-Ray and ultrasound showed high small intestinal obstruction
and target sign which indicates intussusception. An emergency exploratory laparotomy was performed.
The invagination was found at colocolica with lead point was hypertrophic lymphoid tissue in mesentery.
The biopsy showed non-specific chronic lymphadenitis. She was fully recovered and discharged 5 days
after surgery. Ten months later, she had similar symptoms frequent vomitus, but had no flatus or defecation,
and suffered high fever (390C). The abdomen was distended and had no bowel sounds. The ultrasound
revealed target sign again, which suggested recurrent intussusception. The exploratory relaparotomy found
invagination at ileocecal with lead point Meckel diverticulum. The biopsy showed Meckel diverticulum
with non-specific chronic inflammation. She had eventful recovery and discharged 10 days after surgery.
Conclusion Intussusception is an emergent condition, as obstruction of the blood supply to the intestine
may result in bowel infarction, perforation, and even death. Surgery was performed compared to therapeutic
enema because of signs of intestinal obstruction. Recurrent intussusception is a common sequel after the first
intussusception. The incidence of recurrence after surgery is reported up to 5.4%. The prognosis is generally
good if diagnosed immediately and got prompt treatment.
Keywords: recurrent; intussusception; Meckel diverticulum; target sign

KONIKA XVIII Abstract Book 163