Page 53 - Abstract Book KONIKA 18

Cardiology

O-CAR-007
Determining the Diagnostic Value of Echocardiography
in Evaluating Pulmonary Hypertension in Congenital Heart Diseases

Putri Amelia , Mulyadi M. Djer , Najib Advani , Rubiana Sukardi , David Soeliongan Waworuntu 4
1
3
2
2
Department of Child Health, Faculty of Medicine, Universitas Sumatera Utara, Medan, North Sumatera ,
1
Universitas Indonesia, Jakarta , and Universitas Sam Ratulangi, Manado, North Sulawesi ,
2
4
Center of Integrated Cardiac Service, Dr. Cipto Mangunkusumo Hospital, Jakarta , Indonesia
3

Abstract
Background Right heart catheterisation remains the gold standard to diagnose pulmonary hypertension
in CHD patients. Availability and cost of catheterisation are common problems in the developing world.
Recent studies showed that echocardiography could be considered an alternative method to assess pulmonary
hypertension because it is non-invasive, safe and accessible. Objective To determine the diagnostic value
of echocardiography in evaluating pulmonary hypertension in CHD patients. Methods This study was a
cross-sectional study with a total of 48 CHD patients aged under 18 suspected of pulmonary hypertension,
with 22 males and 26 females. The investigation was conducted in Dr. Cipto Mangunkusumo Hospital
from January until December 2020. All subjects were initially assessed with echocardiography and then
underwent right cardiac catheterisation to confirm the diagnosis of pulmonary hypertension. The data were
then recorded and analysed. We estimated the sensitivity, specificity and other diagnostic values while also
performing Bland-Altman analysis to determine the agreement between echocardiography and catheterisation.
Results The sensitivity and specificity of echocardiography in diagnosing pulmonary hypertension were 71.1%
and 70%, respectively. Echocardiography showed a significant change in pre-test and post-test probability,
which were 79.2% to 90%. There was a moderate correlation between the results of the two tests (rho: 0.38,
P=0.0077). The Bland-Altman analysis found -8.9 mmHg bias with 95% limits of agreement from -44.9
to 27.2 mmHg. Conclusion Echocardiography shows a considerable diagnostic capacity in determining
pulmonary hypertension, although it remains inferior to cardiac catheterisation. Echocardiography should
be considered as an alternative method in screening and diagnosing pulmonary hypertension.
Keywords: congenital heart disease; echocardiography; pulmonary hypertension; right heart
catheterization

KONIKA XVIII Abstract Book 7