Page 48 - Abstract Book KONIKA 18

Allergy Immunology

O-AI-003
Impact of Covid-19 Pandemic on the Care of
Pediatric Allergy Immunology Outpatients in A Tertiary Hospital

Endah Citraresmi, Nurul Iman Nilam Sari
Department of Child Health, PKIAN RSAB Harapan Kita, Jakarta, Indonesia

Abstract
Background The COVID-19 pandemic began to hit Indonesia since March 2020. Patient services have
become hampered, both because of the difficulty of patients accessing hospital services, as well as the
difficulty of hospitals providing optimal services for non-COVID-19 patients. In addition, there are
concerns and reluctance of patients to come to the hospital during the pandemic. Objective To describe the
impact of the COVID-19 pandemic on the care of pediatric immunological allergy patients at a national
referral hospital. Methods A cross-sectional study, comparing the services of pediatric allergy immunology
outpatients before (from March 2019 to February 2020) and during (from March 2020 to February 2021)
the COVID-19 pandemic at PKIAN RSAB Harapan Kita. Results Data showed a 46.5% decrease in the
number of visits between two periods (before compared to during COVID-19 pandemic period). The largest
decrease was found in April and May 2020 (57.1 % and 67.6%). The decrease was more found in patients with
self-financing/other health insurance than patients with national health insurance/BPJS (56.6% vs. 42.1%).
Pediatric allergy immunology patients are chronic disease patients who require regular visits because they
require routine medication. It was found a decrease in the number of patients who routinely control >10
times per year from 4.9% to 1.6%. Conclusion The COVID-19 pandemic has affected the care of pediatric
allergy immunology patients by decreasing the number and the frequency of patient visits. This decrease in
visits needs to be followed up by making efforts to maintain continuity of patient treatment.
Keywords: patient care; pediatric allergy immunology; COVID-19 pandemic

O-AI-004
Outcomes and Side Effects of Subcutaneus Immunotherapy
in Children with Asthma: A Preliminary Report

1
Sumadiono , Amalia Setyati , Cahya Dewi Satria , Muchammad Fahrul Udin ,
1
2
1
Alifa Novia Febriani1, Jatmiko Edy Nugroho 1
Department of Child Health, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito
General Hospital, Yogyakarta, Central Java and Department of Child Health, Faculty of Medicine, Universitas Brawi-
1
jaya/Dr. Saiful Anwar Hospital, Malang, East Java , Indonesia
2
Abstract
Background The prevalence of asthma all over the world is 7,2% and 4,5% in Indonesia. Immunotherapy
is beneficial for asthma, but research on immunotherapy has not been widely carried out in Indonesia.
Objective To evaluate the outcome and side effects of subcutaneous immunotherapy in children with asthma.
Methods This randomized control trial was conducted in Dr. Sardjito Hospital, between April to August 2021.
Patients were randomized to receive conventional asthma therapy (C group) and combination of conventional
with subcutaneous house dust mite (HDM) immunotherapy (CI group). Clinical improvement was assessed
by Asthma Control Test (ACT) score and skin prick test. The outcomes were evaluated between initial visit
and 7 weeks of therapy. Statistical analysis by Anova test. Results In 29 subjects, 14 were in C group and
15 were in CI group. Eleven subjects in C group completed the study. There were 57.3 % males and 42.7 %
females. The mean of ACT scores in CI group was more rapidly improve. Conversion of HDM sensitization
to be negative was higher in CI group (40% vs. 0 %). The mean of total allergen sensitization reduction was
higher in CI group (1.67 vs. 0.63). No adverse events were found in this on going study. Conclusion The
mean of ACT score in children with asthma that received immunotherapy was more rapidly improve. The
conversion of HDM sensitization to be negative and the mean of total allergen sensitization reduction were
better. No adverse event were found.
Keywords: asthma; child; immunotherapy; asthma control test; HDM

2 KONIKA XVIII Abstract Book