Page 50 - Abstract Book KONIKA 18

Cardiology

O-CAR-001
Clinical Outcomes of COVID-19 in Children with Cardiac Disease
at Mohammad Hoesin Hospital Palembang

Arif Budiman, Ria Nova, Deny Salverra Yosy
Department of Child Health, Faculty of Medicine Universitas Sriwijaya, Mohammad Hoesin General Hospital,
Palembang, South Sumatera, Indonesia

Abstract
Background COVID-19 can manifest as mild to severe disease. Children with cardiac disease are high-
risk population for severe manifestation. The outcome may differ among different health facilities. It is
suspected that there is a correlation between the SARS-CoV-2 PCR Ct-value and the severity of the disease.
Objective To determine the clinical outcome of COVID-19 in children with cardiac disease at Mohammad
Hoesin Hospital Palembang. Methods Medical records of children with cardiac disease who were hospitalised
for COVID-19 from March 2020 to July 2021 at Mohammad Hoesin Hospital Palembang were analysed for
clinical data, laboratory findings and outcomes. Results There were 98 children with confirmed COVID-19;
eight (8.1%) had cardiac disease. Six of 8 patients with congenital cardiac defects and 2 of 8 patients with
rheumatic heart disease were found. There were 4 of 8 children with cardiac decompensation symptoms,
2 of 8 patients with pneumonia, and 2 of 8 patients with no symptoms. The SARS-CoV-2 PCR Ct-value
varies from 17 to 37.5. Two of 8 patients died, but there was a correlation between Ct-value and mortality rate
of COVID-19 in children with cardiac disease (r 0.354; P=0.786). Conclusion The COVID-19 in children
with cardiac disease has a relatively high mortality rate. There was weak correlation between SARS-CoV-2
PCR Ct-value and mortality rate of COVID-19 in children with cardiac disease.
Keywords: clinical outcome; COVID-19; children with cardiac disease; Ct-value

O-CAR-002
Comparison of Lipid Profiles in Pediatric Patients with Cyanotic and Acyanotic
Congenital Heart Diseases

Fifi Febria Ningsih, Hafaz Zakky Abdillah, Selvi Nafianti
Department of Child Health, Faculty of Medicine, Universitas Sumatera Utara, Medan, North Sumatera, Indonesia
Abstract
Background Congenital heart disease (CHD) is a heart defect that is existing at birth. The incidence of
CHD is about 0.8% of every child born. Dyslipidemia is a lipid metabolism disorder characterized by an
increase or decrease in plasma lipids. Some data show that CHD is associated with dyslipidemia in children.
Examination of lipid profiles in patients with CHD can be used to determine risk factors for atherosclerosis.
Objective To determine the difference of the lipid profile in patients with cyanotic and acyanotic CHD.
Methods This was cross-sectional research on 60 pediatric patients with CHD who came to Haji Adam
Malik Hospital from December 2020 to March 2021. Sampling was carried out using consecutive sampling
techniques. Unpaired T-test analysis and Mann-Whitney test were performed to assess the comparison
between variables. Results All CHD patients totalled 60 subjects, there were 26 subjects with a diagnosis
of cyanotic CHD and 34 subjects with a diagnosis of acyanotic CHD. In cyanotic CHD, the type of TOF
was the most (76.9%), while the most common type of acyanotic CHD was VSD and PDA, each of them
32.4%. In the results of an examination of lipid profiles in both groups, only LDL values were found to be
significant (P<0.05). Conclusion There was a significant difference in LDL levels between cyanotic and
acyanotic CHD. Low density lipoprotein level in cyanotic CHD is lower than in acyanotic CHD. But there
is no significant difference in the incidence and risk factors of dyslipidemia in both groups.
Keywords: children; congenital heart disease; dyslipidemia

4 KONIKA XVIII Abstract Book