Page 260 - Abstract Book KONIKA 18

Infection & Tropical Disease

P-ITD-011
Microbial Pattern and Antibiotic Sensitivity
in Pediatric Ward of Dr. M. Djamil General Hospital Padang

Intan Oktapia, Rinang Mariko
Departemen of Child Health, Faculty of Medicine, Universitas Andalas/Dr. M. Djamil General Hospital
Padang, West Sumatera, Indonesia

Abstract
Background Ineffective use of antibiotics may lead to antibiotic resistance. The selection of antibiotics
should be based on the spectrum of causative bacteria patterns and sensitivity to antibiotics. Reporting of
bacterial patterns and sensitivity testing is very important to be carried out annually, especially for patients in
the pediatric ward as a guideline in giving the proper antibiotics and preventing further spread of infection.
Objective To analyze bacteriogical profile in the pediatric ward of Dr. M. Djamil general hospital Padang
in January - December 2020. Methods This was a retrospective descriptive study. Data was obtained from
patient’s medical records and antibiotic sensitivity and resistance test data from the microbiology laboratory
in Dr. M. Djamil general hospital Padang in January – December 2020. Results There were 138 culture
examinations. The number of gram negative and positive bacterias were 83.3% and 16.7% respectively. The
most commonly gram bacterias were Klebsiella pneumonia (28.9%), Escherichia coli (26.1%), Pseudomonas
aeruginosa (7.9%), Staphylococcus epidermidis (7.2%), and Acinetobacter baumannii (3.7%) and mostly
found in feces, urine and blood samples. Gram positive was mostly resistant to erythromycin (22.2%),
trimethoprim-sulfamethoxazole (19%), ciprofloxacin (15.8%) and sensitive to chloramphenicol (17.4%),
vancomycin (15.1%), and tetracycline (12%). Gram negative was resistant to ampicillin (16.5%), ceftriaxone
(12.1%), ceftazidime (11.3%) and sensitive to amikacin (19.8%), meropenem (19.4%) and gentamicin
(10.9%). Conclusion The most common microbes derived from gram negative bacteria was Klebsiella
pneumonia, with a high sensitivity to amikacin, meropenem, and gentamicin.
Keywords: gram bacteria pattern;, antibiotic resistance; antibiotic sensitivity; paediatric ward

P-ITD-012
Trend of Paediatric Cases with COVID-19 in North Sumatera, Indonesia

1
1
Dicky , Kartini Marpaung , Irbah Rhea Alvieda , Mirzan Hasibuan , R. Andika Dwi Cahyadi ,
1
1
1
Ramadhan Bestari , R. Lia Kusumawati , Inke Nadia D. Lubis 1
1
2
Faculty of Medicine, Universitas Sumatera Utara and Universitas Islam Sumatera Utara ,
1
2
Medan, North Sumatera, Indonesia
Abstract
Background In December 2019, atypical pneumonia was reported in Wuhan, China. It is caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which has been named COVID-19. In Southeast
Asia, Indonesia has the highest number of paediatric cases, which may contribute to the spread of the disease.
Objective We describe the epidemiology of COVID-19 cases in Paediatric in North Sumatera province
from May to October 2020. Methods This study included samples from COVID-19 suspect patients from
North Sumatera province. COVID-19 case is confirmed using a RT-PCR, at the Microbiology Laboratory,
Faculty of Medicine, Universitas Sumatera Utara, Medan. The target gene used are E gene (cut-off: <37),
N gene (cut-off <38) and ORF1ab (cut-off <38). We conduct extraction using semi-automatic capacity of 30
samples per machine. The reagent used for both extraction and PCR is Maccura. Data were collected from
May to October 2020. Results A total of 24,689 people were being tested for SARS-CoV-2 infection, with
3,871 (15.6%) individuals were positive for COVID-19. Children aged <18 years were accounted for 362
cases (9.35%) and mostly are 12-15 years by 118 cases (3%). The proportion of positive cases in children
peaked in September up to 15.86%. Male was more predominant, and Medan City had the highest numbers
of positive cases. Conclusion COVID-19 has been detected in all 33 districts in North Sumatera Province.
Children were accounted for a much higher proportion than reported elsewhere in neighboring countries,
and therefore can be the source of transmission to the community.
Keywords: COVID-19; children; epidemiology; north sumatera

212 KONIKA XVIII Abstract Book