Page 291 - Abstract Book KONIKA 18

Neonatology

P-NEO-010
Postnatal Steroid for Bronchopulmonary Dysplasia: A Case Report

Annisa, Adhie Nur Radityo, Gatot Irawan Sarosa
Child Health Department, Faculty of Medicine, Universitas Diponegoro/Dr. Kariadi General Hospital,
Semarang, Central Java, Indonesia
Abstract
Background Preterm infant are at risk for bronchopulmonary dysplasia (BPD) that is an important cause
of morbidity and mortality. One of the recommendation treatments is postnatal steroids. Steroid have
proven beneficial for the management of BPD postnatally due to their anti-inflammatory characteristics.
Objective This report presents postnatal steroid management in preterm infants with bronchopulmonary
dysplasia. Case A baby boy was born with caesarean section by indication of premature rupture of membranes
and twin gestation from a 26-year-old mother with G3P1A1 and 27 weeks of pregnancy. He had spontaneous
breathing at birth but developed respiratory distress syndrome at 20 minutes of life, administered CPAP and
surfactant during on treatment at special care nursery. He had oxygen dependent at 36 weeks postmenstrual
age. He receiving supplemental oxygen ≥25% via low-flow nasal cannula. Therefore, the diagnosed in this
baby was bronchopulmonary dysplasia. Chest X-ray showed bilateral aeration of pulmonary vascular marking.
Echocardiography was however normal. He was managed with postnatal steroid with total cumulative dose
0.89 mg/kg. He responded to treatment and at the day fourth able to off oxygen. Conclusion Postnatal steroid
is useful to treat bronchopulmonary dysplasia (BPD) in preterm infants.
Keywords: postnatal steroid; bronchopulmonary dysplasia; preterm infant

P-NEO-011
Clinical Profiles of Neonates Born to Mothers with COVID-19

Dyah Rahmawanti, Fiva Aprilia Kadi
Department of Child Health, Faculty of Medicine Universitas Padjadjaran/Hasan Sadikin General Hospital,
Bandung, West Java, Indonesia

Abstract
Background Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) causes Coronavirus
Disease-19 (COVID-19). The virus is transmitted mainly via respiratory droplets and/or close contact
between people. A number cases of neonates born to mothers with COVID-19 have been reported. However,
research that describe clinical profile of neonates born to confirmed COVID-19 mothers is still lacking.
Objective To describe the clinical profile of neonates born to mothers with COVID-19 in Dr Hasan Sadikin
General Hospital during the period of June 2020 to June 2021. Methods We conducted a retrospective
observational descriptive study of 174 neonates born to mothers with COVID-19. The mothers were laboratory
confirmed COVID-19 from positive nasopharyngeal swab. Data of study samples were collected from the
registry and analyzed in spreadsheet using Microsoft Office Excel 2019 Software. Results There are 174
neonates included in this study. Laboratory values of most neonates were within normal limit. Ten neonates
had positive SARS-CoV2 nasopharyngeal swab. Among them, five neonates were born prematurely before 37
weeks of gestation and had birth weight below 2500 grams. Four of them showed signs of respiratory distress.
Conclusion Most neonates in this study had no abnormalities of laboratory values. Considering SARS-CoV-2
may have pathogenic potential, screening of neonates born from confirmed COVID-19 mothers is advised.
Keywords: COVID-19; neonates; clinical profile

KONIKA XVIII Abstract Book 243