Page 239 - Abstract Book KONIKA 18

Hemato-Oncology

P-HO-022
Auto Immune Hemolytic Anemia Patients Profiles and Treatment Response
to Corticosteroids in Dr. Kariadi Hospital Semarang

Ingga Ifada, Bambang Sudarmanto, Ariawan
Department of Child Health, Faculty of Medicine Universitas Diponegoro/Dr.Kariadi Hospital,
Semarang, Central Java, Indonesia

Abstract
Background Autoimmune hemolytic anemia (AIHA) is mediated by autoantibodies directed against red
blood cells causing premature erythrocyte destruction. Data on demographic characteristics, descriptions
of laboratory results and treatment responses of AIHA patients have not been widely available in Indonesia.
Objective This study aimed to identify the profile of autoimmune hemolytic anemia patients and their response
to treatment after receiving corticosteroid therapy in the last 5 years at Dr.Kariadi Hospital. Methods This
descriptive study used data from the medical records of AIHA patients at Dr.Kariadi Hospital between
2015-2020 which included: demographic characteristics, symptoms, Coomb test and hematological features,
response to corticosteroid treatment for 1-7 days with a positive response marked by an increase of Hb≥10
g/dL, and the final diagnosis of AIHA patients after treatment. Results From a total of 48 subjects, paleness
is the most common symptom (70.8%). Peripheral blood pictures in 33 subjects examined, showed the
formation of spherocytes (15.2%). Coomb's test on 35 subjects showed a direct result of 3+ (60% of 35
sample) and an indirect result of 1+ (54.3% of 35 sample).The final diagnosis of AIHA subjects was 27.1%
SLE and 4.2% malignancy. AIHA patients who had a positive response to corticosteroid treatment were 77.1%.
Conclusion The majority of AIHA subjects had pale symptoms. The formation of spherocytes is one of
the features of peripheral blood that can be found in AIHA subjects. The proportion of AIHA subjects who
responded positively after treatment was 77.1%. The final diagnosis of AIHA was 27.1% SLE and 4.2%
malignancy.
Keywords: autoimmune hemolytic anemia; profile; corticosteroid; treatment

P-HO-023
Nutritional Status of Acute Lymphoblastic Leukemia Survivors in Manado

Joko Purnomo Heroanto, Stefanus Gunawan, Max F.J. Mantik
Department of Child Health, Faculty of Medicine, Universitas Sam Ratulangi/Prof. Dr. R. D. Kandou Hospital,
Manado, North Sulawesi, Indonesia

Abstract
Background Many studies showed that ALL survivors living in high income countries had high prevalence
of obesity, but there was lack of data in developing countries. Objective To assess nutritional status among
ALL survivors in Manado and compared it between Standard Risk and High Risk. Methods We conduct a
cross-sectional study to ALL survivors who completed chemotherapy in Prof. Dr. R. D. Kandou Hospital
Manado until June 2021. Weight and height data were measured and plotted to appropriate growth chart,
and interpreted based on Waterlow criteria (normal, underweight, overweight, and obesity). The incidence
of nutritional status was compared between SR versus HR using Chi square and p value < 0.05 is considered
statistically significant. Results There were 65 subjects available for analysis; 54% were males and 46% were
females. Fifty-four percent of the subjects were classified as SR and 46% were classified as HR. There is no
significant proportion difference of nutritional status among ALL survivors between SR versus HR. (normal
71% vs. 83%, P=0.820; underweight 6% vs. 0%, P=0.491; overweight 11.5% vs. 10%, P=0.520; obese 11,5%
vs. 7%, P=0.671, respectively). Conclusion Majority of ALL survivors in Manado have a good nutritional
status. There is no significant difference of nutritional status between SR and HR-ALL survivors in Manado.
Keywords: ALL survivors; nutrional status

KONIKA XVIII Abstract Book 191