Page 113 - Abstract Book KONIKA 18

Allergy Immunology

P-AI-021
Wet Wrap Therapy for Children with Moderate Atopic Dermatitis:
A Case Report

Priyanti Kisworini, Rizqi Amalia, Dina Muktiarti
Department of Child Health, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo National General
Hospital, Jakarta, Indonesia

Abstract
Background Atopic dermatitis (AD) is a chronic inflammatory skin condition that had significant negative
impact on quality of life of the affected children and their families. Wet wrap therapy (WWT) is an alternative
method that could be performed to reduce inflammation in children with moderate AD. This method was
not used widely in Indonesia. Objective To report effectivity of WWT in a child with moderate AD. Case A
3-year-6-month-old boy with recurrent itchy erythematosus skin rashes was diagnosed with moderate AD.
Those complaint begin at 11 months old. It often disturbs his daily activities and worsen at sleep time. His
skin appears very dry. There were erythematous plaques, with papules, and oozing in both of his hands and
feet. The lichenified skin lesion was found in arm and knee folds. Despite standard treatment consists of
moisturizer, topical corticosteroids, avoiding allergens and irritants, the outcome was not optimal. He got
repeated oral steroid from previous doctors. We performed WWT for skin lesion on both of his hands and
feet. We instructed the mother to apply topical corticosteroids and moisturizer followed by covering it with
damp socks and dry socks for 8 hours. The WWT was performed for 3 consecutive days while the patient
was sleeping. There were no active lesion after 3 days and patient continued standard treatment for AD.
Conclusion The WWT is effective to improve outcome in children with moderate AD whose don’t achieve
optimal results with standard treatment and can avoid the use of oral steroid.
Keywords: atopic dermatitis; wet wrap therapy; children

P-AI-022
Clinical Characteristic of Childhood-Onset of Systemic Lupus Erythematosus in
Dr. Soetomo Hospital Surabaya
Savitri Kuntari, Azaria Amelia Adam, Ratih Kumala Sari, Diah Budiarti, Zahrah Hikmah,
Azwin Mengindera Putera, Anang Endriyanto
Department of Child Health. Faculty of Medicine Universitas Airlangga.Dr. Soetomo Genera Hospital, Surabaya,
East Java, Indonesia

Abstract
Background It is estimated that around 20% of patients with systemic lupus erythematosus (SLE) have
their onset in childhood and more severe clinical features. Objective To describe clinical profiles, laboratory
features, and management of childhood-onset of SLE. Methods This descriptive retrospective study was
conducted at Pediatric Allergy and Immunology outpatient clinic of Dr. Soetomo Hospital, Surabaya. Data
were collected from medical record between years 2014 and 2019, and met the criteria of American College
of Rheumatology 1997 for SLE, were enrolled in this study. Microsoft Excel and SPSS 21 were used for data
analysis. Results Sixty-eight patients of SLE was found predominantly in females (78%). The median age at
onset was 9 years. Only 5 patients had family history of autoimmune disease. The clinical manifestation in
different organs were as follows: skin involvement in 38 patients (55.8%), musculoskeletal involvement in
45 patients (66.1%), renal involvement in 19 children (27.9%), hematological abnormalities in 54 patients
(79.4%), cardiovascular involvement in 16 patients (23%), and central nervous system involvement in 24
patients (35.2%). Sixty-two (91.1%) patients had positive anti-dsDNA, 59 (86.7%) patients had positive
ANA-test, and 23 (33.8%) patients had low level of complement. corticosteroids were the most common
treatment for SLE, followed by immunosuppressant. Conclusion Childhood-onset of SLE were predominantly
in females. The most common symptom was hematological abnormalities, followed by musculoskeletal
involvement. Mostly had positive anti-dsDNA. Management included corticosteroid and immunosuppressant.
Keywords: childhood onset; systemic lupus erythematosus; rheumatology; pediatric

KONIKA XVIII Abstract Book 65