Page 283 - Abstract Book KONIKA 18

Infection & Tropical Disease

P-ITD-055
Profiles of the First Wave and the Second Wave of Covid-19
for Children in Bekasi City Hospital

2
Mas Wishnuwardhana 1,2,3 , Glenn Fernandez , Kevin Christian , Siti Rahmah , Charles Antoni ,
1,2
1,2
2
Tri Yanti 1,2,3 , Dina Siti Daliyanti , Thomas Harry Adoe , Adrienta , Mira 1
1,2
1
1,2
2
Department of Child Health, Chasbullah Abdulmadjid Hospital, Bekasi, West Java1, Universitas Kristian Indonesia ,
and Universitas Trisakti , Jakarta, Indonesia
3
Abstract
Background Covid-19 Second Wave has begun from June-July 2021, mostly caused by a newly discovered
SARS-CoV-2 D type. Most children infected with SARS-CoV-2 have presented with mild-flu like symptoms,
but a few patients are in critical condition. and other causes such as parental occupation, and family history
of vaccination. Objective To describe profile of the first and the second wave of COVID-19 in children.
Methods This study was a descriptive study, at the Bekasi City Hospital. With 35 patient form the first wave
and 35 patient from the second wavem of Covid-19. secondary data was taken from the status of Covid-19
patients who were treated in children department of Bekasi City Hospital. Results Many Covid-19 patients
were found to live in Bekasi City (57.1%), with underweight nutritional status (42.8%), and the majority of
parenting occupation Work from Office (62.80%), Family not yet vaccinated (71.4%). And also there was
no significant difference with chief complain and laboratory result in the first or second wave. The Patient
treated by only antiviral (oseltamivir) on the first wave, and Antibiotic,Antiviral, zink, Multivitamin, and
Supportif for the second wave. Conclusion There was an influence comparison between the characteristics of
pediatric patients with Covid-19 in the first wave and the second wave. However, in the second wave, there
was an influence between families who have not been vaccinated against covid on the number of cases in
children. The therapy given includes opseltamivir on the first wave, and for the second wave is antibiotics,
Antiviral (oseltamivir, favipiravir and remdesivir), zinc, multivitamins and other supports.
Keywords: covid-19; children; treatment; vaccination

P-ITD-056
Overview of Antibiotic Use and Incidence of Extended Spectrum Beta
Lactamases after Ceftriaxon Restriction Policy in Pediatrics
at Dr. Kariadi Hospital

Nisa Alifia, MMDEAH Hapsari
Department of Child Health, Faculty of medicine, Universitas Diponegoro/Dr. Kariadi Hospital,
Semarang, central Java, Indonesia

Abstract
Background The number of antibiotic resistance in the world is high. The use of broad-spectrum antibiotics,
especially cephalosporins and fluoroquinolones may lead to extended spectrum betalactamase (ESBL)
bacterial growth in hospitals, with treatment failure and high mortality. Early control of ESBL and adequate
treatment are essential in patient management. Ceftriaxon Restriction Policy as part of The Antimicrobial
Stewardship Programs at Dr Kariadi Hospital Semarang has been implemented since the end of 2018.
Objective To describe the use of quantitative antibiotics and the incidence of ESBL before and after Ceftriaxon
restriction policy implementation in pediatric at Dr Kariadi Hospital. Methods This is a cross-sectional study
of retrospective data from 2018 to 2020 conducted in pediatric patients over 28 days of age. Antibiotic data
is seen from the calculation of the defined daily dose (DDD) of each antibiotic. The culture results included
all samples taken from the patient. Results The most common antibiotics used are ceftriaxon, ampicillin,
ampicillin sulbactam, and gentamicin. The use of ceftriaxone (DDD 10.47-5.30-4.50), ampicillin (DDD
4.4-0.63-0.91), and gentamicin (DDD 3.90-1.61-1.21) was decreased after the Ceftriaxon restriction policy
(2019-2020), while the use of ampicillin sulbactam (DDD 0.12-4.77-6.32) was increased. The results of
ESBL culture from 2018-2020 were 67.8%, 58% and 66.3% respectively. The majority of ESBL culture
results in 2020 were obtained from sputum cultures (30%). Conclusion There is a decrease in the use of
ceftriaxone and 2 other antibiotics after the Ceftriaxon restriction policy implementation at Dr. Kariadi
Hospital Semarang, in line with the decline in ESBL culture results.
Keywords: antibiotics; ceftriaxon; ESBL

KONIKA XVIII Abstract Book 235