Page 246 - Abstract Book KONIKA 18

Hemato-Oncology

P-HO-036
Health-Related Quality of Life in Children with Acute Lymphoblastic Leukemia:
A Comparison between High Risk and Standard Risk, A Cross-Sectional Study

Chatryn Soetanto, Irene Revania Maryauw, Sianne Sandjoto, Max Mantik, Stefanus Gunawan
Department of Child Health, Prof. Dr. R.D. Kandou General Hospital/Faculty of Medicine Universitas Sam Ratulangi,
Manado, North Sumatera, Indonesia

Abstract
Background The treatment for childhood acute lymphoblastic leukemia (ALL) can be aggressive
and long-term. This might impact Health-Related Quality of Life (HRQoL) among these patients.
Objectives To assess the HRQoL in children with ALL in Manado, Indonesia. Methods We conducted a
cross-sectional study from May 2018 to July 2021. We used the PedsQL 3.0 Cancer Module™ instrument
to interview parents and/or children aged 2 to 18 years old in the maintenance chemotherapy phase of ALL
treatment. Based on NCI criteria, samples were divided into standard risk (SR) and high risk (HR) group.
Results There were 92 participants (38 SR and 54 HR). In SR group, 28 children (74%) had good HRQoL
(mean PedsQL score 76.132 ± 2.0925). There were 13 children (24%) HR group had good HRQoL (mean
PedsQL score 66.111 ± 1.0349). The ‘procedural anxiety’ subscale revealed the lowest score in both groups.
Both groups showed ‘perceived physical appearance’ subscale as the highest score. There was a significant
difference in the HRQoL between children with HR ALL and SR ALL (P<0.001). Conclusion ALL children
in SR group had a better HRQoL than those of HR group.
Keywords: acute lymphoblastic leukemia; children; health-related quality of life

P-HO-037
The Epidemiology of Pediatric Cancer in Dr. Soetomo General Hospital Surabaya
Diah Kusuma Arumsari, Andi Cahyadi
Division of Hematology Oncology, Department of Child Health, Dr. Soetomo General Hospital Surabaya,
East Java, Indonesia
Abstract
Background The prevalence of childhood cancer In Indonesia showed an increase from 1.4 per 1000
population in 2013 to 1.79 per 1000 population in 2018. The epidemiology in Indonesia may not describe
the real number because there are still many unreported cases due to lack of statistics and registry.
Objective To know the epidemiology of pediatric cancer in Dr. Soetomo General Hospital Surabaya.
Methods This observational study collected data from medical records of pediatric cancer patients at inpatient
and outpatient clinic at Dr. Soetomo General Hospital Surabaya, from January to June 2021. Patients were
aged 0-18 years who newly diagnosed with cancer and never received treatment before. The data examined
were sex, age group, and type of cancer. Cancer in children was classified as hematology malignancy
(leukemia) and solid tumors. Results There are 91 patients, consist of 60.4% male and 39.6% female. The
patients were 1.1% infant (under 1 year old), 53.9% toddler (1-5 years old), 37.3% kids (5-13 years old),
and 7.7% adolescent (13-18 years old). The most common type of cancer was leukemia (71%), consist of
59.3% (ALL), 6.6% (AML), 5.5% (CML). Retinoblastoma was the most common type of solid tumor (9.9%),
followed by osteosarcoma, lymphoma, rhabdomyosarcoma (3.3%), then neuroblastoma and nephroblastoma
(2.2%). Only 76.9% patients underwent chemotherapy, the remainder refused chemotherapy (7.7%) or died
before starting chemotherapy (15.4%). Conclusion Most pediatric cancer patients are male, aged 1-5 years.
The most common type of cancer is leukemia, followed by retinoblastoma, osteosarcoma, lymphoma.
Keywords: epidemiology; pediatric cancer

198 KONIKA XVIII Abstract Book