Page 183 - Abstract Book KONIKA 18

Endocrinology

P-ENDO-013
Glycemic Control in Children with Type 1 Diabetes Mellitus in the Beginning
and After 9 Months of the Covid-19 Pandemic in Surakarta

Yanuar Ariefudin, Annang Giri Moelyo
Department of Child Health, Faculty of Medicine Universitas Sebelas Maret, Moewardi General Hospital,
Surakarta, Central Java, Indonesia

Abstract
Background Type 1 Diabetes Mellitus (T1DM) is a chronic disease that requires glycemic control. Before
Covid-19 pandemic, glycemic control was not only influenced by parents, but also by the involvement of
teachers and friends at school. In previous studies, there were significant differences in glycemic control
between before and during the Covid-19 pandemic. Objective To analyze the difference in the mean HbA1c
between T1DM children in the beginning and after 9 months of the Covid-19 pandemic. Methods This is a
cross sectional design. This study was conducted in Moewardi General Hospital, at July 2021, and comprised
all children with T1DM who were school-age using insulin at least 6 months before Covid-19 pandemic.
Results of the HbA1c in the early 3 months and after 9 months of the Covid-19 pandemic were recorded.
Paired t-test used to analyze the data. Results 14 subjects were tested for HbA1c in the early 3 months and
after 9 months of the Covid-19 pandemic. The average HbA1c in the early 3 months pandemic 9.93% and 9
months pandemic 9.93%. The paired t-test did not show any significant difference of HbA1c in the beginning
and after 9 months of the Covid-19 pandemic (P>0.05). Conclusion Based on DCCT, glycemic control in
children with T1DM during the Covid-19 pandemic in Surakarta were the high risk category.
Keywords: glycemic control; type 1 diabetes mellitus; HbA1c; Covid-19 pandemic

P-ENDO-014
Importance of Early Diagnosis and Prompt Treatment
of Vitamin D Deficiency Rickets

Lilis Siti Asiyani, Suryono Yudha Patria, Madarina Julia
Departement of Child Health, Faculty of Medicine, Public Health and Nursing.Universitas Gadjah Mada/
Dr. Sardjito General Hospital, Yogyakarta, Central Java, Indonesia
Abstract
Background Rickets is a disease caused by a failure in the mineralization of the growth plate and osteoid
matrix of the growing bones. Objective To emphasize the importance of early diagnosis and prompt treatment
of rickets to prevent deformities. Case Illustration We reported a 17 years old boy presenting with knock-
knees, limp walking, and twisted body trunk. His limb abnormalities were first detected when he was 3 years
old, and got worse since then. There was no consanguity history; his parents and siblings had normal statures.
Physical examinations observed short stature, severe scoliosis, severe bilateral genus valgum, swelling of
wrist and ankle joints, frontal bossing, rachitis rosary and prominent Harrison’s grooves. The biochemical
tests found severe Vitamin D deficiency (25-OHD 4.6 ng/mL), hypocalcemia, hypophosphatemia, and
elevated parathyroid hormone (PTH) (140.3 pg/mL). The radiology findings showed widening, cupping,
and fraying of the metaphysical regions, osteopenia, and genus valgum. Patient received vitamin D 6000 U/
th
day and calcium supplementation. After 5 months of treatment, the PTH normalized (37.7 pg/mL). On the
th
9 month of treatment, due to persistently low level of 25-OHD, the vitamin D was increased to 10,000 IU/
day. Clinical improvement of the deformity was still not clearly observed. Conclusion Vitamin D deficiency
rickets is a preventable disease. Early diagnosis and prompt treatment are important to prevent subsequent
deformity affecting quality of life. Late treatment leads to severe deformities that is difficult to correct.
Keywords: rickets; vitamin D deficiency; genu valgum; deformity

KONIKA XVIII Abstract Book 135