Page 273 - Abstract Book KONIKA 18

Infection & Tropical Disease

P-ITD-035
Neutrophil To Lymphocyte Count Ratio With Monosit To Lymphocyte Ratio To
Determine Diarrhea Bacterial with Nonbacterial in Children

Nico Adi Saputra, Gilbert Sterling Octavius, Tan Gabriella Heidina Handoko,
Gabriella Triana Ayu, Valentina, Friecelie Natalie Sutarna, Andry Juliansen
Department of Child Health, Faculty of Medicine, Universitas Pelita Harapan, Karawaci, Tangerang,
Banten, West Java, Indonesia
Abstract
Background Diarrhea is the second leading cause of death among children under the age of 5 with the septic
bacterial infection have an increased proportion of the deaths. Because of that, increased demand for a way
to help efficient diagnosis in terms of cost and time. Objective This study goal was to evaluate usage of the
neutrophil to lymphocyte ratio (NLR) and the Monocyte to Lymphocyte Ratio (MLR) to determine bacterial
and nonbacterial diarrhea. Methods A cross-sectional study was done to 235 inpatients that previously admitted
with diarrhea, who had a complete blood count examination. The data were analyzed statistically with Mann-
Whitney and ROC curve. Results Mann-Whitney test showed that NLR (P=0.01) was significant compared
to MLR (P=0.111). The ROC curve value for NLR was 0.664 with cutoff value 1.62 with sensitivity 63.4%
and specificity 56.2%. Conclusion The NLR can be used to determine bacterial and nonbacterial diarrhea
to help diagnose compared to the MLR.
Keywords: NLR; neutrophil lymphocyte ratio; MLR; monosit lymphocyte ratio; bacterial diarrhea;
nonbacterial diarrhea

P-ITD-036
A Case of Early Congenital Syphilis with Good Outcome
Related to Proper Management

Olga Vicetria Putrie Purba, Riyadi, Anggraini Alam, Djatnika Setiabudi
Department of Child Health, Faculty of Medicine, Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital,
Bandung, West Java, Indonesia

Abstract
Background Congenital syphilis is an ancient disease that continues to plague infants worldwide.
Approximately, 10-12% of infants born to mothers with positive serology for syphilis would die if untreated.
A wide spectrum of severity exists, from inapparent infection to severe cases that are clinically apparent
at birth. Objective This case report aims to remind about the importance of screening for syphilis and
proper management that will provide the good outcome. Case A baby boy was born from P1A0 mother
spontaneously with the history of syphilis. The mother was 17 years old, works as song guide at karaoke
place, not married, and diagnosed with syphilis at 8 months of pregnancy when antenatal screening through
lab result of reactive Venereal Disease Research Laboratory test (VDRL) and reactive Treponema pallidum
Particle Hemagglutination Assay (TPHA). The mother already received therapy with penicillin procaine
once. There were no found skeletal and skin deformity at birth, but lab result showed VDRL titer fourfold
higher than the mother’s titer so the patient was treated with procaine penicillin G 50.000 units/kg/dose IM
in a single daily dose for 10 days. The next serological follow up examination at 3 months after the initial
treatment show that VDRL was nonreactive and at 6 months follow up found both VDRL and TPHA were
nonreactive. Conclusion It is possible that a baby with congenital syphilis won’t have any symptoms at
birth. But without treatment, the baby may develop serious problems.
Keywords: congenital syphilis; management; maternal screening

KONIKA XVIII Abstract Book 225