Page 224 - Abstract Book KONIKA 18

Gastroenterohepatology

P-GEH-028
Correlation between Recurrent Abdominal Pain with H. pylori Infection
in Children

Miky Akbar, Supriatmo, Winra Pratita
Department of Child Health, Faculty of Medicine, Universitas Sumatera Utara/Haji Adam Malik General Hospital,
Medan, North Sumatera, Indonesia

Abstract
Background Abdominal pain in children is a very common symptom in preschool and school age. It can occur
repeatedly in children called recurrent abdominal pain (RAP). Recurrent abdominal pain is often associated
with Helicobacter pylori infection. Helicobacter Pylori Stool Antigen (HPSA) is one of the non-invasive
methods that easily done to determine the presence of Helicobacter pylori infection in children with RAP.
Objective To determine correlation between RAP and H. pylori infection in children. Methods Cross
sectional study in children aged 2-18 years old according to inclusion and exclusion criteria. HPSA was
performed by patient's stool using a rapid immunochromatographic test as a qualitative detection of H. pylori
in human feces. To assess the difference between two variable using chi square test (X ). Results A total of
2
56 children were analyzed. HPSA examination results showed there were 36 children with positive HPSA
and 20 children with negative HPSA. Symptoms of RAP occurred in 16 children (44.4%) in the group with
positive HPSA while in the group with negative HPSA, all children occurred RAP. Significant associated
was found between RAP with H. pylori infection (P<0.001). Conclusion Significant correlation was found
between RAP with H. pylori infection in children.
Keywords: recurrent abdominal pain; Helicobacter pylori; children

P-GEH-029
Differences of Hemoglobin and Transferrin Level between Helicobacter pylori
Gastritis and Non-Helicobacter pylori Gastritis in Children

Hensen, Supriatmo, Oke R .Ramayani
Department of Child Health, Faculty of Medicine, Universitas Sumatera Utara/Haji Adam Malik Hospital, Medan,
North Sumatera, Indonesia
Abstract
Background Gastritis can reduce the hemoglobin level. Based on previous study, gastritis resulted from
Helicobacter pylori infection often correlated to anemia as the capability of Helicobacter pylori to obtain
iron from hemoglobin and transferrin. Objective To analysis the differences of hemoglobin and transferrin
level between Helicobacter pylori gastritis and non-Helicobacter pylori gastritis in children. Methods A cross
sectional study was conducted with subject ages from 2 to 18 years, diagnosed with Helicobacter pylori
gastritis and non-Helicobacter pylori gastritis based on CLO test. Blood sample was taken from subjects
to evaluate hemoglobin and transferrin level. Results 54 subjects with gastrointestinal complaints were
recruited. Subjects were divided into 2 groups based on CLO test, 32 subjects with Helicobacter pylori and
22 subjects without Helicobacter pylori. From blood sample analysis, mean hemoglobin and transferrin
value from Helicobacter pylori group was 10.9 gr/dL and 253.5 mg/dL. Meanwhile, mean hemoglobin and
transferrin value from non-Helicobacter pylori group was 10.8 gr/dL and 261.9 mg/dL. (P>0.05). Conclusion
No difference in hemoglobin and transferrin level between Helicobacter pylori gastritis and non-Helicobacter
pylori gastritis in children.
Keywords: gastritis; Helicobacter pylori; hemoglobin; transferrin

176 KONIKA XVIII Abstract Book