Page 105 - Abstract Book KONIKA 18

Allergy Immunology

P-AI-005
Clinical Characteristic of Juvenile Idiopathic Arthritis in Dr. Soetomo Hospital
Surabaya

Diah Budiarti, Azaria Amelia Adam, Ratih Kumala Sari, Zahrah Hikmah,
Azwin Mengindera Putera Lubis, Anang Endryanto
Department of Child Health. Faculty of Medicine Universitas Airlangga/Dr. Soetomo General Academic Hospital,
Surabaya, East Java, Indonesia

Abstract
Background Juvenile idiopathic arthritis (JIA) is a common chronic rheumatic disease that limits the daily
activities and productivity of the patient. By definition, disease onset prior to the age of 16 years and arthritis
persisting for longer than 6 weeks are required criteria for diagnosis of JIA. Objective To determine the
clinical characteristics of children with JIA at a tertiary health care center in Surabaya, Indonesia Methods A
retrospective study was conducted in the pediatric Allergy and Immunology outpatient clinic of Dr. Soetomo
General Hospital, Surabaya to identify patients with a diagnosis of JIA according to ILAR criteria, between
year 2014 and 2019. Results A total of 27 children with JIA were included in this study. JIA was found 52%
in girl and 48% in boy. The median age of disease onset was 8 years. Polyarticular was the most predominant
subtype in 14 (51%) patients, followed by oligoarticular type in 11 (40%) patients. Nine (33.3%) patients
were rheumatoid factor positive. The common chief complaints were arthralgia, swollen and stiffness of
joint, and fever. Six (22.2%) children came with joint contracture. Only 1 patient presenting with uveitis
and subluxated lens. Oral NSAID such as ibuprofen was the most common therapeutic choice, followed by
oral steroids, and methotrexate. Conclusion This study provides a clinical characteristics data of JIA with a
higher frequency of oligoarthritis that can improve the understanding and therapeutic approach.
Keywords: juvenile idiopathic arthritis; children; rheumatic disease

P-AI-006
Clinical Characteristic of Children with Henoch Scholein Purpura in
Dr. Soetomo Hospital Surabaya

Diah Budiarti, Azaria Amelia Adam, Ratih Kumala Sari, Zahrah Hikmah, Azwin Mengindera Putera Lubis
Department of Child Health. Faculty of Medicine Universitas Airlangga/Dr. Soetomo General Academic Hospital,
Surabaya, East Java, Indonesia
Abstract
Background Henoch Schonlein Purpura (HSP) is a systemic vasculitis disease that is common in children
whose major manifestations include non-thrombocytopenic purpura, arthritis or arthralgia, abdominal pain,
and renal involvement. Objective To describe demographic, clinical profile, and management of HSP in
children. Method All patients were diagnosed as HSP at pediatric Allergy and Immunology outpatient clinic
of Dr. Soetomo General Academic Hospital, Surabaya between years 2014 and 2019 were enrolled in this
study. Clinical characteristics, laboratory findings, and therapy of all children were evaluated descriptively
retrospectively. Microsoft Excel was used for data analysis. Results A total 40 children had enrolled in this
study. Male to female ratio was 1.2:1. The median age was 9 years. Twenty-eight (70%) patients were referral
from other hospitals. The first symptom was non-thrombocytopenia skin purpura, mainly concentrated at
the lower extremities and buttocks, following with gastrointestinal symptoms, and arthritis knee and ankle
joint, both in 31 (77.5%) patients. Dominant gastrointestinal symptoms were abdominal pain, vomiting, and
bloody diarrhea. Microscopic hematuria and proteinuria were in 7 (17.5%) patients. An increased ESR was
reported in 22 patients (55%). ASO titer was higher in 5 children (12.5%). Seventy percent of patients were
given NSAID, followed by oral steroid in 17 (42.5%) patients. An allergic diet was given to 11 patients.
Conclusion HSP in children had equal gender distribution. Non-thrombocytopenia skin purpura at lower
extremities and buttocks was most common symptom. Management of HSP included NSAID, oral steroids,
and an allergic diet.
Keywords: children; Henoch Schonlein Purpura; abdominal pain

KONIKA XVIII Abstract Book 57