Page 364 - Abstract Book KONIKA 18

Nutrition & Metabolic Diseases

P–NMD–013
Diet and Physical Activity of Adolescent Nutritional Status
at SMPN 10 Cimahi City

Khoirunnisa, Salli Fitriyanti, Andri Andrian Rusman
Faculty of Medicine Universitas Jenderal Ahmad Yani, Cimahi, West Java, Indonesia

Abstract
Background Adolescence is an important phase of life because of the biological, emotional, and social
growth. Physical growth will increase nutritional need. In such age, many activities is done after the school
time so it will cause irregular meal time and increase the physical activities, which will increase the risk of
underweight. Objective To find out the prevalence, eating and physical activity pattern of adolescent with
undernutrition in SMPN 10 Cimahi. Methods This study used descriptive method which used 10-15 years
old adolescent with undernutrition consisted as the subjects and used 75 adolescent picked by proportional
stratified random sampling. The data gathered are the students' height, weight, interviews about eating and
physical activity pattern which are presented in tables and narrations. Results This study showed 10,72 %
underweight respondent, the mean energy of both gender were less than EER, 49,33 % respondent had 2
main food in a day, and 61,33% respondent ate snacks twice a day in small portion. All the respondent ate
incomplete. Constituents of food, with the mean energy intake in breakfast and snacks between breakfast
and lunch were bigger than lunch and dinner, 40% respondent had very few physical activity. Conclusion
From this study we can conclude that most teenager had low energy intake, irregular mealtime, small portion,
and incomplete nutrients of food.
Keywords: adolescent; underweigh; meal pattern; physical activity pattern

P–NMD–014
X-linked Adrenoleukodystrophy:
A Case Report in A Child with Typical Clinical Features

M. Taufik Perwira Wicaksono, Moretta Damayanti,Masayu Rita Dewi, Raden Muhammad Indra, Julius Anzar
Department of Child Health, Faculty of Medicine Universitas Sriwijaya/Dr. Mohammad HoesinGeneral Hospital,
Palembang, South Sumatera, Indonesia
Abstract
Background X-linked adrenoleukodystrophy (X-ALD) is a rare genetic disorder caused by mutations in the
ABCD1 gene responsible for the breakdown of very-long-chain fatty acids (VLCFAs) in a human body. The
VLCFAs accumulation may be toxic to myelin and adrenal glands. Prognosis of X-ALD is poor, with severe
disability and death between two and three years after onset. Objective To report a rare case of X-ALD. Case
A 10-years old boy showed regression of some neurological functions started from eight months before.
Gradually, he lost his previously acquired skills, such as understanding speech and handwriting. Three months
later, he developed hearing loss, diminished vision, weakness, and stiffness of the limbs. At one month before
admission, he had become totally disabled. There was no consanguinity. Tendon reflexes were brisk and
pathological reflexes were present. Nutritional status was moderate malnutrition. Brain Magnetic Resonance
Imaging (MRI) revealed a symmetrical hyperintense lesion on flair, non-homogenous T2 and iso-intense T1,
suggested leukodystrophies at lateral paraventricular white matters, posterior corn and temporal-bilateral to
corpus callosum and pons. Examination of VLCFAs showed decreased docosanoic acid (C22:0), increased
hexacosanoic acid (C26:0), high ratios of C24/C22 (1,67) and C26/C22 (0,11). Serum cortisol level was
very low (0,1 gr/dl) and was treated with oral hydrocortisone (20 mg/m2/day). Treatment was supportive,
including enteral nutrition and physiotherapy. Conclusion Neurological regression accompanied by adrenal
insufficiencymight be the early sign of X-ALD. Moreover, typical findings on Brain MRI and VLCFAsprofiles
will support the diagnosis.
Keywords: X-linked adrenoleukodystrophy; X-ALD; brain MRI; VLCFAs

316 KONIKA XVIII Abstract Book