Page 354 - Abstract Book KONIKA 18

Neurology

P-NEU-035
Characteristics of Pediatric Epilepsy Patients
at Abdul Moeloek General Hospital, Lampung Province

Roro Rukmi Windi Perdani, Debby Cinthya D.V, Emeraldha Theodorus, Dara Marissa Widya Purnama
Departement of Child Health, Medical Faculty of Universitas Lampung, Abdul Moeloek General Hospital,
Lampung, Indonesia

Abstract
Background Epilepsy is the most common chronic neurological disorder affecting approximately 10.5
million children and 80% live in developing countries. Electroencephalography (EEG) can be used for
evaluating therapy. Objective To determine the characteristics of pediatric epilepsy patients in Abdul Moeloek
Hospital, Lampung. Methods it was a descriptive observational study. There were 29 epileptic children who
had routine medication at Abdul Moeloek Hospital from January 2019 to February 2021 by consecutive
sampling technique. Data were obtained from medical records and EEG. The research was approved by
Ethical Committee of Medical Faculty of Universitas Lampung. Results there were more boys (58.45%),
and the most age was 6-year-old (31%). All respondents did not have family history of epilepsy, yet 17 %
had history of other seizure. Approximately 13.7% had asphyxia as risk factor. Cerebral palsy (17.3%),
microcephaly (17.3%), and brain atrophy (3.4%) were comorbidities. The most common type of seizures
was general tonic-clonic (62%). Many subjects had onset under 6-month-old and between 1-6 -year-old.
All of them had more than 1 times seizure with less than 5 minutes of duration. The EEG showed 48.3%
with epileptic waves. About 89.7% got valproic acid monotherapy and 48.2% showed an improvement.
Conclusion majority respondents were boys, 6-year-old and asphyxia as risk factor. Many respondents had
seizure onset at less than 6-month-old and between 1-6 year. The frequency of the seizure was more than 1
times in a day and less than 5 minutes with generalized tonic-clonic. Cerebral palsy, microcephaly, and brain
atrophy were common comorbidities. Most respondents had epileptic waves, got valproic acid and got better.
Keywords: characteristic; children; epilepsy

P-NEU-036
Timing of Diagnosis and Clinical Characteristics of Pediatric Brain Tumor
at Mohammad Hoesin Hospital, Palembang
Ari Fibrianto, Raden Muhammad Indra, Masayu Rita Dewi
Department of Child Health, Faculty of Medicine Universitas Sriwijaya/Dr. Mohammad Hoesin General Hospital,
Palembang, South Sumatera, Indonesia
Abstract
Background Brain tumors are the second most common pediatric malignancy and the most common
cause of cancer-related mortality and morbidity. Local socio-economic conditions can cause delayed
diagnosis, advanced disease at presentation, and late referrals, ultimately affecting the patient's outcome.
Objective To identify the timing of diagnosis, clinical features, management, and outcome of children with
brain tumors. Methods Medical records of children with confirmed brain tumors admitted to Mohammad
Hoesin Hospital Palembang between January 2020 and June 2021 were reviewed. We collected data
regarding the timing of diagnosis, clinical findings, management, and outcome. Results A total of 44 patients
(male 65.9%) with brain tumors were identified, with a mean age of 116.9 (SD 50.0) months. The median
duration of symptoms before diagnosis was 3 (range 2.6-8.5) months. In 24 (54.5%) children, the diagnosis
was made more than two months after onset. The predominant site was infratentorial 25 (56.8%), with
medulloblastoma 12 (26.7%) as the most common tumor found. Most patients underwent surgical resection
34 (75.6%). Radiation was given to 24 (54.5%) children. Twenty-two (50.0%) patients died, and 3 (6.8%)
were lost to follow-up. There was an increase in mortality in children whose diagnosis was made more than
six months after onset (RR 1.56;95% CI 0.92-2.64). Impaired consciousness at admission was predictive
for mortality (RR 2.03; 95%CI 1.1 to 3.75). Conclusion The majority of children with intracranial tumors
have delayed diagnosis. Most cases are infratentorial. The mortality rate is high, which may be affected by
the diagnostic delay.
Keywords: brain tumor; childhood; clinical features; timing of diagnosis

306 KONIKA XVIII Abstract Book