Page 325 - Abstract Book KONIKA 18

Nephrology

P-NEP-013
Primary Hypertension in 6 Pediatric Patients with Corona Virus Disease 19:
Case Series at COVID-19 Emergency Hospital Wisma Atlet Kemayoran
(RSDC WAK) with One Month Follow Up

1
Nia Fitriyani , Tiona Romauli , Fitria Mahrunnisa 2
2
1
2
General Practitioner and Pediatrician , COVID-19 Emergency Wisma Atlet Kemayoran Hospital,
Jakarta, Indonesia
Abstract
Background Binding of SARS-CoV-2 Spike protein and ACE2 might cause a downregulation of ACE2 that
lead to RAAS disorders and decreased of ACE2 expression and activity result in shift towards the ACE/
Ang II pathway to propagate acute lung injury in COVID-19. Hence, it is a crucial clinical concern for
pediatrician in treating hypertension children with COVID-19 although there is not enough evidence yet
that children with hypertension are at increased risk of SARS-CoV-2 infection or more-severe COVID-19.
Objective To report our cases with hypertension in pediatric with COVID-19 since January-May 2021.
Case There were 6 children confirmed COVID-19 incidentally detected hypertension. Five of them were
malnourished, three were obese and two were overweight, with mean age 15 years old. Family history of
hypertension confirmed in all children. Four of them had mild symptoms and two were asymptomatic. There
were no comorbidities found other than hypercholesterolemia present in 3 children. All patients showed normal
chest radiograph. All patients received multivitamin, anti-hypertension of ARB and CCB (candesartan and
amlodipine), symptomatic therapy, dietary treatment for malnourished children and statin for 3 children. All
children showed good recovery both clinically and blood pressure with close monitoring. One month after
treatment, there was 1 patient that still had high blood pressure. Conclusion Children and adolescents may
be at higher risk for cardiovascular disease, especially in malnourished children. therefore, blood pressure
examination is recommended to measure routinely especially during pandemic. Future researches are still
needed due to high prevalence of hypertension in children and better management.
Keywords: pediatric; COVID-19; hypertension

P-NEP-014
Characteristic of Urinary Acidity in Pediatric Patient
with Urinary Tract Infection

M. Amri Kautsar, Dedi Rachmadi, Ahmedz Widiasta
Department of Child Health, Faculty of Medicine Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital,
Bandung, West Java, Indonesia

Abstract
Background Urinary Tract Infection (UTI) is the most common cause of bacterial infection in pediatric.
Inadequate diagnosis and delayed treatment of UTI has an impact to the pediatric’s quality of life. Urinary
acidity is an important indicator to represent the renal tubules function, the existence of infectious process,
and the underlying pathogenic microorganism involved. This study evaluates any factors related to urinary
acidity changes in pediatric patient with UTI. Objective To describe the characteristic of urinary PH in
hospitalized pediatric patient with urinary tract infection in Dr. Hasan Sadikin General Hospital during
the period of 1st Mei 2021 to 30th June 2021. Methods We conducted a retrospective and observational
descriptive study of all hospitalized pediatric patient aged 1 – 18 years with the diagnosis of UTI during the
period of 1st May to 30th June 2021. Data of all study samples was collected from medical record. Urinary
acidity was classified to acidic pH (<5.5), normal pH (5.5-7.5), alkaline pH (>7.5) based on WHO criteria.
Results From 30 pediatric patients enrolled in this study, mean urinary pH was 6,75. Most patients (86.67%)
showed normal urinary pH (5.5-7.5). Only one (3.34%) showed more acidic urinary pH (less than 5.5) and
three patients (10%) showed more alkaline pH (more than 7.5). Conclusion Most pediatric patients with UTI
showed normal urinary acidity. However, a few patients revealed urinary acidity abnormality (more acidic
or alkaline) which may be related to different underlying microorganism involved.
Keywords: urinary pH; pediatric; urinary tract infection

KONIKA XVIII Abstract Book 277